Hexarelin
A synthetic GH secretagogue derived from GHRP-6; not FDA-approved, circulating as a research chemical, and prohibited in sport under WADA S2.
What it is
Hexarelin is a synthetic hexapeptide growth-hormone secretagogue, structurally derived from GHRP-6, that stimulates endogenous GH release via GH-secretagogue receptors.S1
Marketed as
Hexarelin is promoted for muscle growth, fat loss, recovery, and cardiovascular benefit. These are marketing claims, not established effects.S1
Regulatory status (US)
Hexarelin is not FDA-approved for human therapeutic use; its evidence base is predominantly preclinical with limited human data.S1 It circulates as a research chemical rather than a licensed medicine (see caveat on its compounding- framework status).S1
Hexarelin's precise position within FDA's compounding framework should be confirmed against FDA's current listings; unlike GHRP-6/GHRP-2 it is not clearly in the active Category 2 table. S1
Around the world
Hexarelin is not an approved medicine; it is available internationally as a research-use-only substance rather than a marketed drug.S1
Evidence
Human data are limited; effects on the GH-IGF-1 axis have been observed in early studies, but hexarelin is not an approved therapy and its marketed body-composition and cardiovascular claims are not established.S1
Anti-doping
As a GH secretagogue, hexarelin (also called examorelin) is prohibited at all times under WADA S2.S2S3
Safety
As an unapproved research peptide, hexarelin has limited human safety data, and use falls outside any regulated finished-drug oversight; the general concerns for unapproved GH-axis peptides apply.S1
What's changing
The item to track is any clarification of hexarelin's status within FDA's compounding framework.S1
Sources
Every reference below is a primary source cited in this entry, drawn from the approved corpus.
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01
Hexarelin (Wikipedia — chemistry, GH-secretagogue class, development status)en.wikipedia.org · Tertiary reference
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02
WADA — The Prohibited List (current International Standard)wada-ama.org · Anti-doping standard
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03
WADA S2 — Peptide Hormones, Growth Factors, Related Substances and Mimetics (list reference)drugs.com · Anti-doping list reference
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